This was a fun idea I cooked up with InuHoshi-to-DarkPen after I watched Across the Spider-Verse. It's some of my favorite younger characters from Friendship is Magic re-imagined as some of the best young heroes from Marvel and DC!
Spike has a bit in common with the Miles Morales Spider-Man, trying to find his own way and make his own mark despite being pulled in a couple of different directions.
Smolder is the Gwen Stacy Spider-Woman (also known as Ghost-Spider or Spider-Gwen). She's the cool big sis-mentor who shows Spidey the ropes (the webs?) and comes from a place where she's used to keeping secrets about herself and is a bit slow to open up. She's also rad as all get out and can kick seven kinds of tail.
Ocellus is the Jaime Reyes Blue Beetle. A decent, kind, hard-working kid trying to do the right thing while showing that even an instrument of pain and destruction (i.e. the scarab) can be reformed into a force for good, shunning violence and cruelty; which is not unlike what the post-Season 6 changelings are all about.
They're my favorites of the Student Six (and Spike) and these are some of my favorite heroes, so there you go.